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Antibody response to Bordetella avium was measured in serum and mucosal secretions of experimentally infected turkeys. Two-day-old turkeys were inoculated with B. avium, and four inoculated turkeys and four uninoculated control birds per trial were euthanatized weekly from 1 through 8 weeks postinoculation (PI). Maternal antibody of the IgG isotype, present in all 2-day-old birds sampled, decreased to background levels by 3 weeks of age. Antibody (IgG, IgM, IgA) was detected in serum, tracheal washings, and lacrimal secretions in response to B. avium infection. Regardless of the sample site and isotype, antibody levels peaked at 4-6 weeks PI and then decreased rapidly from 6 to 8 weeks PI. In general, IgM and IgA levels peaked earlier (4-5 weeks PI) but declined more rapidly than IgG levels. Numbers of B. avium in the trachea peaked at 2-3 weeks PI and then decreased rapidly from 4 to 8 weeks PI. Even though no direct causal relationship could be determined, the results indicate that an increasing level of antibody in serum, tracheal washings, and lacrimal secretions is temporally associated with clearance of B. avium from the trachea.
P Suresh, and
L H Arp, and
E L Huffman
October 1984,
American journal of veterinary research,
P Suresh, and
L H Arp, and
E L Huffman
May 1989,
Veterinary pathology,
P Suresh, and
L H Arp, and
E L Huffman
January 2000,
Avian diseases,
P Suresh, and
L H Arp, and
E L Huffman
January 1991,
Memorias do Instituto Oswaldo Cruz,
P Suresh, and
L H Arp, and
E L Huffman
January 1986,
Avian diseases,
P Suresh, and
L H Arp, and
E L Huffman
January 1998,
Avian diseases,
P Suresh, and
L H Arp, and
E L Huffman
December 2004,
Infection and immunity,
P Suresh, and
L H Arp, and
E L Huffman
August 1990,
Veterinary microbiology,
P Suresh, and
L H Arp, and
E L Huffman
July 1990,
Journal of virology,
P Suresh, and
L H Arp, and
E L Huffman
January 2006,
Clinical and vaccine immunology : CVI,
