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OBJECTIVE To assess the extent of a measles epidemic in a secondary school. METHODS Retrospective and questionnaire investigation. METHODS Secondary school, Bilthoven. METHODS Questionnaire followed by laboratory testing for measles and other infectious diseases with exanthema. RESULTS The response rate was 99% (935/949 pupils, aged 12-21 years, vaccination rate 92%). Seventy-seven students underwent laboratory investigations. Measles virus was isolated in 2 suspected patients. Thirty-three of 37 patients with clinical or laboratory criteria of measles had been vaccinated. Complications of measles were not detected. Infection was also detected in patients with relatively few or atypical symptoms. The protective efficacy of measles vaccine could be determined because the attack rate of the school population was less than 5%. CONCLUSIONS Primary failure of the measles vaccine might be the cause of the minor epidemic but the results do not cast doubt on the efficacy of the current measles vaccination programme.
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
March 1995,
Nederlands tijdschrift voor geneeskunde,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
March 1977,
The New England journal of medicine,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
November 2005,
PLoS medicine,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
November 1996,
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
January 2015,
Virus research,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
July 1992,
Journal of clinical microbiology,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
December 1965,
Northwest medicine,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
December 1993,
Atencion primaria,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
January 2003,
Vaccine,
M J van Eijndhoven, and
H C Rümke, and
A Bosman, and
W C van Dijk, and
R Hirsch, and
R S van Binnendijk
January 1999,
MMWR. Morbidity and mortality weekly report,
