Biomaterial Database

[Measles epidemic in a school population. Effectiveness of the vaccine]. 1993

R Cosín Borobio

Centro de Salud de San Leonardo de Yagüe, Soria.

OBJECTIVE To describe the distribution of the illness according to the school students' measles vaccination status and to assess its effectiveness. METHODS Analytical study of a retrospective cohort. METHODS Two schools within the Base Health Area of San Leonardo de Yagüe, Soria. METHODS 410 school students between 3 and 14. 314 were included in the study sample. RESULTS The overall vaccination rate was 81.8% and was higher among lower age groups. The overall incidence rate was 18.5%; 9.7% in those vaccinated and 57.9% in those not vaccinated. The incidence rates increased with age, 5.5% for the 3-6 and 24.5% for the 11-14 age groups. Vaccine effectiveness was measured by Relative Risk (5.9) and Attributable Fraction (83.2%), with a statistically significant association between non-vaccination and the occurrence of measles. CONCLUSIONS As measles vaccination is highly effective, it would be worthwhile to increase vaccine coverage to 93.5-96%, so that group immunity within a community can be attained and so transmission of the disease be avoided.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008457	Measles	A highly contagious infectious disease caused by MORBILLIVIRUS, common among children but also seen in the nonimmune of any age, in which the virus enters the respiratory tract via droplet nuclei and multiplies in the epithelial cells, spreading throughout the MONONUCLEAR PHAGOCYTE SYSTEM.	Rubeola
D008458	Measles Vaccine	A live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had measles or been immunized with live measles vaccine and have no serum antibodies against measles. Children are usually immunized with measles-mumps-rubella combination vaccine. (From Dorland, 28th ed)	Vaccine, Measles
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004196	Disease Outbreaks	Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.	Outbreaks,Infectious Disease Outbreaks,Disease Outbreak,Disease Outbreak, Infectious,Disease Outbreaks, Infectious,Infectious Disease Outbreak,Outbreak, Disease,Outbreak, Infectious Disease,Outbreaks, Disease,Outbreaks, Infectious Disease
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective