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The concentrations of active agent were determined in the bile and serum after oral administration of ampicillin and pivampicillin to 12 patients 7-9 days after surgical revision of the common bile duct. Orally, pivampicillin is more rapidly absorbed, maxima of active agent and the mean serum concentrations are higher compared with ampicillin. The rate of absorption and serum concentrations after giving ampicillin and pivampicillin depend on the type of diet. Pivampicillin produces higher concentrations of active agent in the bile of the common bile duct more rapidly than ampicillin. The mean concentration of active substance in the bile is distinctly above the serum concentrations.
W Peitsch, and
R Ansorg, and
K Burkhardt
January 1974,
European journal of clinical pharmacology,
W Peitsch, and
R Ansorg, and
K Burkhardt
January 1972,
Acta tuberculosea et pneumologica Belgica,
W Peitsch, and
R Ansorg, and
K Burkhardt
December 1975,
European journal of clinical pharmacology,
W Peitsch, and
R Ansorg, and
K Burkhardt
June 1974,
Arzneimittel-Forschung,
W Peitsch, and
R Ansorg, and
K Burkhardt
March 1973,
Pediatrics,
W Peitsch, and
R Ansorg, and
K Burkhardt
November 1975,
Arzneimittel-Forschung,
W Peitsch, and
R Ansorg, and
K Burkhardt
January 1973,
Chemotherapy,
W Peitsch, and
R Ansorg, and
K Burkhardt
May 1976,
Clinical pharmacology and therapeutics,
W Peitsch, and
R Ansorg, and
K Burkhardt
July 1989,
Drug and therapeutics bulletin,
W Peitsch, and
R Ansorg, and
K Burkhardt
January 1979,
Therapie,
