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Two cases are described of severe Mycoplasma pneumoniae infection in whom cross-reacting antibodies developed to a glycopeptide antigen of Micropolyspora faeni. The antibodies were predominantly IgG, although some IgM was detected. Precipitin responses to M. faeni were detected for 4 months after the initial illness in one case, and 1 month in the second case. The cross-reacting antibodies were closely related to the antibodies responsible for the complement fixation reaction to M. pneumoniae. It is suggested that a common polysaccharide antigen may exist on the surface membranes of M. pneumoniae and M. faeni. Initial studies of the frequency of the development of cross-reacting antibodies in M. pneumoniae infection suggest it is uncommon. Atypical cases of farmer's lung should be investigated to exclude M. pneumoniae infection.
B H Davies, and
J H Edwards, and
A Seaton
January 1994,
American journal of industrial medicine,
B H Davies, and
J H Edwards, and
A Seaton
April 1978,
The Journal of allergy and clinical immunology,
B H Davies, and
J H Edwards, and
A Seaton
January 1985,
Antonie van Leeuwenhoek,
B H Davies, and
J H Edwards, and
A Seaton
April 1980,
The Journal of allergy and clinical immunology,
B H Davies, and
J H Edwards, and
A Seaton
November 1981,
Infection and immunity,
B H Davies, and
J H Edwards, and
A Seaton
January 1979,
International archives of allergy and applied immunology,
B H Davies, and
J H Edwards, and
A Seaton
January 1977,
International archives of allergy and applied immunology,
B H Davies, and
J H Edwards, and
A Seaton
December 1972,
Clinical allergy,
B H Davies, and
J H Edwards, and
A Seaton
December 1983,
The American review of respiratory disease,
B H Davies, and
J H Edwards, and
A Seaton
July 1989,
Allergy,
