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Diarrhea developed in five newborn rhesus monkeys (Macaca mulatta) inoculated orally on the first day of life with the human reovirus-like agent of infantile gastroenteritis. Incubation period ranged from 2-5 days; virus particles were detected in stools in association with illness, and virus shedding lasted between 1 and 3 days. Virus derived from monkeys that developed illness following inoculation was infectious for other monkeys but did not induce diarrhea which could be associated temporally with virus shedding. Viral antigens were also detected in tissues of the grossly abnormal small intestine of an acutely-ill monkey. Serum antibody responses were demonstrated in two of the ill animals by complement-fixation and/or immunofluorescence.
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
January 1976,
The Journal of infectious diseases,
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
August 1976,
Infection and immunity,
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
November 1975,
Lancet (London, England),
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
May 1975,
Lancet (London, England),
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
January 1974,
Research in veterinary science,
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
August 1977,
Lancet (London, England),
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
January 1976,
Intervirology,
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
November 1977,
Journal of clinical microbiology,
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
April 1975,
Lancet (London, England),
R G Wyatt, and
D L Sly, and
W T London, and
A E Palmer, and
A R Kalica, and
D H Van Kirk, and
R M Chanock, and
A Z Kapikian
February 1977,
Journal of clinical microbiology,
