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In order to verify the utility of the captopril test (CT) in diagnosing renal artery stenosis we performed a prospective study in 94 consecutive patients (40 females, 54 males, mean age 52.4 +/- 12.3 years) suspected of having renovascular hypertension and with a serum level of creatinine < 2 mg/dl. Antihypertensive drugs were withdrawn one week before the CT or, if this was considered unsafe, patients were treated with nifedipine or diltiazem (53 subjects; 56.4%). We used renal angiography and the Muller criteria to interpret the CT. Our results were as follows: sensitivity, 92%; specificity, 96%; positive predictive value, 88%; and negative predictive value, 97%. In our study a simplified criterion for positive CT-postcaptopril plasma renin activity > 10 ng/mL/h-provided a similar diagnostic value. We conclude that the captopril test is a useful screening test for the detection of renal artery stenosis in selected hypertensive patients and that it can also be reliably performed in patients who are taking calcium antagonists.
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
March 1994,
Angiology,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
January 1989,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
December 1990,
American journal of hypertension,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
November 1993,
The Netherlands journal of medicine,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
January 1992,
Journal of nuclear biology and medicine (Turin, Italy : 1991),
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
September 1995,
Journal of human hypertension,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
April 1988,
Diabetic medicine : a journal of the British Diabetic Association,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
January 1988,
Nephron,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
August 1993,
Archives des maladies du coeur et des vaisseaux,
M B Secchi, and
S Mancarella, and
S C Wu, and
L Bettazzi, and
M Pietra, and
G Loche, and
E M Merlo
March 1991,
Giornale italiano di cardiologia,
