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By means of electron microscopic autoradiography we demonstrated a radioactivity in mice spleen lymphocytes after a common cultivation for 1 h with 3H-uridine marked autologian macrophages, washed profoundly. The radioactivity in lymphocytes is small after contact with unstimulated macrophages and is markedly increased after common cultivation with antigen stimulated macrophages. A transfer of RNA molecules of macrophages into lymphocytes is supposed.
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