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Assignment of the phosducin (PDC) gene to human chromosome 1q25-1q32.1 by somatic cell hybridization and in situ hybridization. 1993
R S Sparkes, and
R H Lee, and
T Shinohara, and
C M Craft, and
T Kojis, and
I Klisak, and
C Heinzmann, and
J B Bateman
Department of Medicine, Jules Stein Eye Institute, UCLA Center for the Health Sciences 90024.
Phosducin is a soluble photoreceptor phosphoprotein that probably modulates phototransduction in the retina and thus qualifies as a potential candidate gene for retinitis pigmentosa. Using both human/mouse somatic cell hybrids and in situ hybridization to human metaphase chromosomes, we have mapped this gene to chromosome 1q25-1q32.1.
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