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Superoxide Dismutase (SOD) activity was compared in rabbit peritoneal macrophages (ambient PO2 approximately 15 Torr) and alveolar macrophages (ambient PO2 approximately 100 Torr) and in brain, lung, cardiac muscle, and skeletal muscle of chromically hypoxic mice(ambient PO2 approximately 50 Torr) and normoxic mice (ambient PO2 approximately 150 Torr). Peritoneal macrophages (PM) have significantly less SOD activity than alveolar macrophages (AM) (PM: 2.94 +/- 0.49 (mean +/- SD); AM:6.03 +/- 1.60 units-mg protein -1 (P less than 0.01)). SOD activity of lung and brain homogenates from the hypoxic mice was significantly less than from the normoxic controls. Heart and skeletal muscle SOD activities were not significantly different. These studies show that limitations of O2 supply are associated with reductions in SOD and are consistent with the thesis that SOD plays an important role in protection against oxygen toxicity in mammalian systems.
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
August 2002,
Nihon rinsho. Japanese journal of clinical medicine,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
August 1999,
Nihon rinsho. Japanese journal of clinical medicine,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
June 1993,
Rinsho byori. The Japanese journal of clinical pathology,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
January 1992,
Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
June 1992,
Sangre,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
October 2002,
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
July 1998,
Neuroscience letters,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
September 1993,
American journal of obstetrics and gynecology,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
March 1996,
Journal of radiation research,
J Liu, and
L M Simon, and
J R Phillips, and
E D Robin
August 1997,
Neuroscience letters,
