Biomaterial Database

Dual infection with canine distemper virus and infectious canine hepatitis virus (canine adenovirus type 1) in a dog. 1993

Y Kobayashi, and K Ochiai, and C Itakura

Department of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

A 72-day-old, female, Golden Retriever dog showed anorexia, coughing, nasal discharge, diarrhea and hematochezia, and died on the 15th clinical day. Pathological examination revealed dual infection with canine distemper virus (CDV) and canine adenovirus (CAV). CAV inclusion bodies occurred only in the liver, and biliary and respiratory system, whereas CDV inclusions were demonstrated in the visceral organs systematically. The CAV inclusions were associated with multifocal hepatocellular necrosis and edematous swelling of the wall of the gall bladder, suggesting infectious canine hepatitis virus (canine adenovirus type 1) infection.

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D004216	Distemper	A name for several highly contagious viral diseases of animals, especially canine distemper. In dogs, it is caused by the canine distemper virus (DISTEMPER VIRUS, CANINE). It is characterized by a diphasic fever, leukopenia, gastrointestinal and respiratory inflammation and sometimes, neurologic complications. In cats it is known as FELINE PANLEUKOPENIA.	Canine Distemper,Distemper, Canine,Canine Distempers,Distempers,Distempers, Canine
D004283	Dog Diseases	Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.	Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005260	Female		Females
D006516	Adenoviruses, Canine	Species of the genus MASTADENOVIRUS that causes fever, edema, vomiting, and diarrhea in dogs and encephalitis in foxes. Epizootics have also been caused in bears, wolves, coyotes, and skunks. The official species name is Canine adenovirus and it contains two serotypes.	Canine Adenoviruses,Hepatitis Virus, Infectious Canine,Canine Adenovirus,Canine Infectious Hepatitis Virus,Hepatitis Virus, Canine,Infectious Canine Hepatitis Virus,Canine Hepatitis Virus,Canine Hepatitis Viruses,Hepatitis Viruses, Canine,Viruses, Canine Hepatitis
D006524	Hepatitis, Viral, Animal	INFLAMMATION of the LIVER in animals due to viral infection.	Viral Hepatitis, Animal,Animal Viral Hepatitides,Animal Viral Hepatitis,Viral Hepatitides, Animal
D000257	Adenoviridae Infections	Virus diseases caused by the ADENOVIRIDAE.	Adenovirus Infections,Infections, Adenoviridae,Infections, Adenovirus,Adenoviridae Infection,Adenovirus Infection,Infection, Adenoviridae,Infection, Adenovirus
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia