BIOMAT Database Logo BIOMAT Database Logo

Crystallization and preliminary X-ray diffraction studies of Theiler's virus (GDVII strain). 1993

K S Toth, and C X Zhang, and H L Lipton, and M Luo
Department of Microbiology, University of Alabama, Birmingham 35294.

Theiler's murine encephalomyelitis virus (TMEV) is a member of the picornavirus family. Mice infected with TMEV serve as models for the study of human neurological diseases including multiple sclerosis. Preparations of the GDVII strain of Theiler's virus have been crystallized using the hanging drop technique. When exposed to high intensity synchrotron radiation, these monoclinic crystals diffracted X-rays to at least 3.0 A resolution. The unit cell has a C-centered lattice with dimensions: a = 575.2 A, b = 324.0 A and c = 558.4 A, beta = 108.2 degrees. The molecular mass and cell dimensions imply that there is an entire virus particle per asymmetric unit, suggesting the presence of 60-fold non-crystallographic redundancy. This GDVII crystal form appears to be suitable for high-resolution structure determination.

UI MeSH Term Description Entries
D003460 Crystallization The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Crystalline Polymorphs,Polymorphism, Crystallization,Crystal Growth,Polymorphic Crystals,Crystal, Polymorphic,Crystalline Polymorph,Crystallization Polymorphism,Crystallization Polymorphisms,Crystals, Polymorphic,Growth, Crystal,Polymorph, Crystalline,Polymorphic Crystal,Polymorphisms, Crystallization,Polymorphs, Crystalline
D004680 Maus Elberfeld virus A strain of ENCEPHALOMYOCARDITIS VIRUS, a species of CARDIOVIRUS, usually causing an inapparent intestinal infection in mice. A small number of mice may show signs of flaccid paralysis. Encephalomyelitis Virus, Murine,Mouse Elberfeld Virus,Mouse Encephalomyelitis Virus,Murine Encephalomyelitis Virus,Encephalomyelitis Virus, Mouse
D014961 X-Ray Diffraction The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Xray Diffraction,Diffraction, X-Ray,Diffraction, Xray,Diffractions, X-Ray,Diffractions, Xray,X Ray Diffraction,X-Ray Diffractions,Xray Diffractions

Related Publications

K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of tobacco necrosis virus.
August 1987, Journal of molecular biology,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Proinsulin: Crystallization and preliminary x-ray diffraction studies.
August 1970, Proceedings of the National Academy of Sciences of the United States of America,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of psoriasin.
January 1997, Acta crystallographica. Section D, Biological crystallography,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of the influenza C virus glycoprotein.
September 1996, Acta crystallographica. Section D, Biological crystallography,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of human RANTES.
September 1994, Journal of molecular biology,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of recombinant staphylokinase.
May 1996, Acta crystallographica. Section D, Biological crystallography,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of coxsackievirus B1.
February 1992, Journal of molecular biology,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of soybean agglutinin.
April 1984, Journal of molecular biology,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of human angiostatin.
March 2002, Acta crystallographica. Section D, Biological crystallography,
K S Toth, and C X Zhang, and H L Lipton, and M Luo
Crystallization and preliminary X-ray diffraction studies of human catalase.
September 1999, Acta crystallographica. Section D, Biological crystallography,
Copied contents to your clipboard!