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Employing Capture ELISA, we determined the level of the circulating soluble egg antigen-antibody complex (SEAIC) in sera from mice infected with Schistosoma japonicum for 7 weeks and then treated the infected mice with praziquantel (100 mg/kg body weight). It was noted that the serum SEAIC level in treated mice dropped gradually after treatment. There was a significant decrease in 13 out of 15 mice in serum SEAIC levels at five weeks after treatment, OD value dropped from 0.358 +/- 0.074 to 0.165 +/- 0.049 (P < 0.01). The serum SEAIC level in 10 mice declined to disappear (OD < 0.097) by the 7th week after treatment. By contrast, no significant changes in serum SEAIC levels were found in the non-treated mice, the serum SEAIC level in the control group maintained moderately high (OD = 0.266 +/- 0.076) till the end of the observation.
G Shi, and
Z Xu, and
C Fu, and
X Weng
January 1998,
Transactions of the Royal Society of Tropical Medicine and Hygiene,
G Shi, and
Z Xu, and
C Fu, and
X Weng
December 2008,
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases,
G Shi, and
Z Xu, and
C Fu, and
X Weng
June 2022,
Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control,
G Shi, and
Z Xu, and
C Fu, and
X Weng
September 1985,
Yao xue xue bao = Acta pharmaceutica Sinica,
G Shi, and
Z Xu, and
C Fu, and
X Weng
April 1987,
Japanese journal of medical science & biology,
G Shi, and
Z Xu, and
C Fu, and
X Weng
January 1995,
Parasitology research,
G Shi, and
Z Xu, and
C Fu, and
X Weng
April 1988,
The Japanese journal of experimental medicine,
G Shi, and
Z Xu, and
C Fu, and
X Weng
January 1992,
Transactions of the Royal Society of Tropical Medicine and Hygiene,
G Shi, and
Z Xu, and
C Fu, and
X Weng
March 1988,
Zhongguo yao li xue bao = Acta pharmacologica Sinica,
G Shi, and
Z Xu, and
C Fu, and
X Weng
July 2009,
Acta tropica,
