Biomaterial Database

An unusual case of nicotine poisoning. 1977

H Garcia-Estrada, and C M Fishman

Acute nicotine poisoning by enema is an uncommon event. A review of the last 70 years of the English and Spanish medical literature has failed to reveal a case of nicotine poisoning by enema in an adult. The use of tobacco enemas in children to treat intestinal parasites has been reported as a cause of poisoning and death. We have recently treated an adult for acute nicotine poisoning from a tobacco enema. This unusual case allowed us to observe some of the complex pharmacologic responses of the body to nicotine.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009538	Nicotine	Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.	Nicotine Bitartrate,Nicotine Tartrate
D004733	Enema	Insertion of a solution or compound through the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.	Enemata,Enemas,Enematas
D005947	Glucose	A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.	Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man