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The change in activity of three disaccharidase enzymes (maltase, sucrase and lactase) was determined according to the method of Dahlqvist during acute rejection in non-immunosuppressed piglet small bowel grafts. In addition, two brush border enzymes, lactase and aminopeptidase, were stained with monoclonal antibodies. Diminishing disaccharidase activity was an early event during rejection. Diminution began 2 days before distinct morphological changes were seen in the mucosal biopsies. Evaluation of disaccharidase activity can thus be used as a confirmatory method in detecting rejection. Reduction in immunohistological staining of lactase and aminopeptidase with monoclonal antibodies and changes in mucosal morphology were observed to progress simultaneously.
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
June 1994,
Transplantation proceedings,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
July 1995,
Journal of pediatric surgery,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
January 1999,
Acta gastro-enterologica Belgica,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
April 1990,
Journal of clinical pathology,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
November 1997,
Molecular biology of the cell,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
March 1979,
Clinica chimica acta; international journal of clinical chemistry,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
August 2003,
Transplant international : official journal of the European Society for Organ Transplantation,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
October 1996,
Transplantation proceedings,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
June 1994,
Transplantation proceedings,
P Kuusanmäki, and
J Lauronen, and
T Paavonen, and
M Pakarinen, and
E Savilahti, and
P Häyry, and
J Halttunen
January 1998,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
