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The carcinogenic potential of tamarind seed polysaccharide was examined in both sexes of B6C3F1 mice. Groups of 50 male and 50 female animals were given diets containing 0, 1.25 and 5% of tamarind seed polysaccharide for 78 wk. Body weight retardation was exhibited by the females in the 1.25 and 5% groups from 34 wk to termination. However, there were no treatment-related clinical signs or adverse effects on survival rate, food and water consumption, haematology findings or organ weights. Detailed histopathological examination also revealed no treatment-related increase in the incidence of any non-neoplastic or neoplastic lesions. These results demonstrated that tamarind seed polysaccharide is not carcinogenic in B6C3F1 mice of either sex.
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
August 1947,
Current science,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
August 1992,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
October 1984,
Gan,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
July 1991,
Carbohydrate research,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
December 1982,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
December 1998,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
September 1991,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
January 2002,
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
September 1989,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
M Sano, and
E Miyata, and
S Tamano, and
A Hagiwara, and
N Ito, and
T Shirai
September 1990,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
