-transparent.png){kind=logo}
The mutation underlying myotonic dystrophy is the expansion of polymorphic CTG repeat in the 3'-noncoding region of the myotonin protein kinase (MtPK) gene mapping to chromosome 19q13.3. A full-length cDNA of human MtPK was cloned and expressed in COS-1 cells. MtPK is recovered from the COS cell extract as a 70 kDa protein, which coincides with the size deduced from the predicted amino acid sequence. Biochemical characteristics of MtPK expressed in COS cells and its expression are investigated.
Related Publications
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
December 1997,
Nihon rinsho. Japanese journal of clinical medicine,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
May 1997,
Bratislavske lekarske listy,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
June 1995,
Proceedings of the National Academy of Sciences of the United States of America,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
March 1995,
Human molecular genetics,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
May 1995,
The Journal of clinical investigation,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
February 1994,
Biochemical and biophysical research communications,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
September 1997,
Genetika,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
July 1998,
Neuroreport,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
July 1994,
Biochemical and biophysical research communications,
S Ishiura, and
N Sasagawa, and
N Saitoh, and
H Koike, and
H Sorimachi, and
K Suzuki, and
M Shimokawa, and
F Usuki, and
H Nakase, and
K Kamakura
April 1993,
Science (New York, N.Y.),
