Biomaterial Database

Types and incidence of human periapical lesions obtained with extracted teeth. 1996

P N Ramachandran Nair, and G Pajarola, and H E Schroeder

Institute of Oral Structural Biology, University of Zurich, Switzerland.

OBJECTIVE To determine (1) the frequency of the incidence of abscess, granuloma, and radicular cyst among human periapical lesions obtained with extracted teeth; and (2) whether periapical cysts occur in two categories when histologically analyzed in relation to the root canals. METHODS A total of 256 lesions were analyzed. The specimens were decalcified and embedded in plastic. Serial sections or step-serial sections were prepared, and the sections were evaluated on the basis of predefined histopathologic criteria. RESULTS The 256 specimens consisted of 35% periapical abscess, 50% granuloma, and 15% cysts. The latter occurred in two categories, the apical true cysts and the apical pocket cysts. CONCLUSIONS These results show (1) the low incidence of radicular cysts among periapical lesions as against the widely held view that almost half of all periapical lesions are cysts; and (2) the occurrence of two classes of radicular cysts. We are of opinion that the pocket cysts may heal after root canal therapy but the true cysts are less likely to be resolved by conventional root canal treatment.

UI	MeSH Term	Description	Entries
D008214	Lymphocytes	White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.	Lymphoid Cells,Cell, Lymphoid,Cells, Lymphoid,Lymphocyte,Lymphoid Cell
D008867	Microtomy	The technique of using a microtome to cut thin or ultrathin sections of tissues embedded in a supporting substance. The microtome is an instrument that hold a steel, glass or diamond knife in clamps at an angle to the blocks of prepared tissues, which it cuts in sections of equal thickness.	Thin Sectioning,Ultramicrotomy,Sectioning, Thin,Sectionings, Thin,Thin Sectionings
D009504	Neutrophils	Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	LE Cells,Leukocytes, Polymorphonuclear,Polymorphonuclear Leukocytes,Polymorphonuclear Neutrophils,Neutrophil Band Cells,Band Cell, Neutrophil,Cell, LE,LE Cell,Leukocyte, Polymorphonuclear,Neutrophil,Neutrophil Band Cell,Neutrophil, Polymorphonuclear,Polymorphonuclear Leukocyte,Polymorphonuclear Neutrophil
D010482	Periapical Abscess	Acute or chronic inflammation of tissues surrounding the apical portion of a tooth, associated with the collection of pus, resulting from infection following pulp infection through a carious lesion or as a result of an injury causing pulp necrosis. (Dorland, 27th ed)	Abscess, Periapical,Alveolar Abscess, Apical,Dentoalveolar Abscess, Apical,Periapical Periodontitis, Suppurative,Periodontitis, Apical, Suppurative,Abscess, Apical Alveolar,Abscess, Apical Dentoalveolar,Abscesses, Apical Alveolar,Abscesses, Apical Dentoalveolar,Abscesses, Periapical,Alveolar Abscesses, Apical,Apical Alveolar Abscess,Apical Alveolar Abscesses,Apical Dentoalveolar Abscess,Apical Dentoalveolar Abscesses,Dentoalveolar Abscesses, Apical,Periapical Abscesses,Periapical Periodontitides, Suppurative,Periodontitides, Suppurative Periapical,Periodontitis, Suppurative Periapical,Suppurative Periapical Periodontitides,Suppurative Periapical Periodontitis
D010484	Periapical Granuloma	Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.	Dental Granuloma,Granuloma, Periapical,Periapical Periodontitis, Chronic Nonsuppurative,Periodontitis, Apical, Chronic Nonsuppurative,Dental Granulomas,Granuloma, Dental,Granulomas, Dental,Granulomas, Periapical,Periapical Granulomas
D010950	Plasma Cells	Specialized forms of antibody-producing B-LYMPHOCYTES. They synthesize and secrete immunoglobulin. They are found only in lymphoid organs and at sites of immune responses and normally do not circulate in the blood or lymph. (Rosen et al., Dictionary of Immunology, 1989, p169 & Abbas et al., Cellular and Molecular Immunology, 2d ed, p20)	Plasmacytes,Cell, Plasma,Cells, Plasma,Plasma Cell,Plasmacyte
D011842	Radicular Cyst	Slow-growing fluid-filled epithelial sac at the apex of a tooth with a nonvital pulp or defective root canal filling.	Periapical Cyst,Periodontal Cyst, Apical,Apical Periodontal Cyst,Apical Periodontal Cysts,Cyst, Apical Periodontal,Cyst, Periapical,Cyst, Radicular,Cysts, Apical Periodontal,Cysts, Periapical,Cysts, Radicular,Periapical Cysts,Periodontal Cysts, Apical,Radicular Cysts
D003648	Decalcification Technique	Removal of minerals from bones during bone examination.	Decalcification Technic,Decalcification Technics,Decalcification Techniques,Technic, Decalcification,Technics, Decalcification,Technique, Decalcification,Techniques, Decalcification
D003786	Dental Pulp Cavity	The space in a tooth bounded by the dentin and containing the dental pulp. The portion of the cavity within the crown of the tooth is the pulp chamber; the portion within the root is the pulp canal or root canal.	Pulp Canal,Pulp Chamber,Root Canal,Cavities, Dental Pulp,Cavity, Dental Pulp,Dental Pulp Cavities,Pulp Cavities, Dental,Pulp Cavity, Dental,Canal, Pulp,Canal, Root,Canals, Pulp,Canals, Root,Chamber, Pulp,Chambers, Pulp,Pulp Canals,Pulp Chambers,Root Canals
D004848	Epithelium	The layers of EPITHELIAL CELLS which cover the inner and outer surfaces of the cutaneous, mucus, and serous tissues and glands of the body.	Mesothelium,Epithelial Tissue,Mesothelial Tissue,Epithelial Tissues,Mesothelial Tissues,Tissue, Epithelial,Tissue, Mesothelial,Tissues, Epithelial,Tissues, Mesothelial