-transparent.png){kind=logo}
Five cases of trisomy 16 confined to the placenta have been detected by invasive procedures (amniocentesis and chorionic villus sampling) after high-risk results for Down syndrome and neural tube defects in a maternal serum screening programme of 6614 consecutive cases. All five pregnancies displayed unusually elevated levels of human chorionic gonadotropin and four out of five also had raised alpha-fetoprotein values. No structural malformation was present but all five pregnancies were complicated by fetal growth retardation, and one by intrauterine death. From our results, we suggest that both amniocentesis and chorionic villus sampling should be considered in the management of cases with high mid-trimester levels of these analytes.
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
December 1992,
Prenatal diagnosis,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
May 1996,
American journal of obstetrics and gynecology,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
August 1997,
Prenatal diagnosis,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
November 1988,
American journal of medical genetics,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
December 2018,
Prenatal diagnosis,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
November 2018,
Prenatal diagnosis,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
August 1990,
Prenatal diagnosis,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
October 1989,
Lancet (London, England),
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
April 2023,
International journal of molecular sciences,
C Groli, and
V Cerri, and
M Tarantini, and
D Bellotti, and
C Jacobello, and
R Gianello, and
R Zanini, and
S Lancetti, and
S Zaglio
July 2009,
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC,
