Progress toward poliomyelitis eradication--People's Republic of China, 1990-1996. 1996


In 1988, the Western Pacific Region of the World Health Organization (WHO) adopted a resolution to eradicate poliomyelitis from the region by the end of 1995. The People's Republic of China has made rapid progress toward this goal by implementing the four WHO-recommended strategies for polio eradication: 1) achieving and maintaining high routine vaccination coverage levels among children aged < 1 year with at least three doses of oral poliovirus vaccine (OPV); 2) administering supplementary doses of OPV to all young children during National Immunization Days (NIDs) to rapidly interrupt poliovirus transmission; 3) establishing sensitive systems of surveillance for acute flaccid paralysis (AFP) and virologic surveillance for poliovirus; and 4) conducting "supplementary immunization activities" (SIAs)--localized campaigns targeted at high-risk areas where poliovirus transmission is most likely to persist at low levels. These strategies have resulted in the apparent interruption of wild poliovirus transmission in China. In 1995, no indigenous wild polioviruses were deteced despite a strengthened surveillance system. This report describes progress toward achievement of the eradication goal and updates the status of polio-eradication efforts in China during 1990-1996.

UI MeSH Term Description Entries
D011051 Poliomyelitis An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) Infantile Paralysis,Polio,Poliomyelitis, Nonpoliovirus,Poliomyelitis, Preparalytic,Encephalitis, Polio,Epidemic Acute Poliomyelitis,Polio Encephalitis,Poliomyelitis Infection,Poliomyelitis, Acute,Acute Poliomyelitis,Acute Poliomyelitis, Epidemic,Infection, Poliomyelitis,Infections, Poliomyelitis,Nonpoliovirus Poliomyelitis,Paralysis, Infantile,Poliomyelitides, Preparalytic,Poliomyelitis Infections,Poliomyelitis, Epidemic Acute,Polios,Preparalytic Poliomyelitis
D011055 Poliovirus Vaccine, Oral A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed) Sabin Vaccine,Oral Poliovirus Vaccine,Vaccine, Oral Poliovirus,Vaccine, Sabin
D002681 China A country spanning from central Asia to the Pacific Ocean. Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014611 Vaccination Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis. Immunization, Active,Active Immunization,Active Immunizations,Immunizations, Active,Vaccinations
D017589 Immunization Programs Organized services to administer immunization procedures in the prevention of various diseases. The programs are made available over a wide range of sites: schools, hospitals, public health agencies, voluntary health agencies, etc. They are administered to an equally wide range of population groups or on various administrative levels: community, municipal, state, national, international. Vaccination Awareness,Vaccination Campaign,Vaccination Promotion,Awareness, Vaccination,Awarenesses, Vaccination,Campaign, Vaccination,Campaigns, Vaccination,Immunization Program,Program, Immunization,Programs, Immunization,Promotion, Vaccination,Promotions, Vaccination,Vaccination Awarenesses,Vaccination Campaigns,Vaccination Promotions

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