-transparent.png){kind=logo}
The levels of lipid peroxidation product (malondialdehyde = MDA) and vitamin C and the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were determined in the liver and its mitochondrial fraction, in the rats 2 and 18 hr after the injection of phorone, a glutathione (GSH) depleting agent. GSH levels decreased in liver homogenate and its mitochondrial fraction after 2 hr of phorone treatment, but these values returned to normal levels at 18 hr. In GSH depleted conditions, hepatic vitamin C levels increased, GSH-Px and SOD activities remained unchanged in mitochondrial and post-mitochondrial fractions. These results indicate that GSH depletion per se does not influence lipid peroxidation and GSH-Px and SOD activities in the liver and the mitochondrial fraction.
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
December 2000,
Japanese journal of cancer research : Gann,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
April 1984,
Experientia,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
December 2007,
The Journal of toxicological sciences,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
August 2005,
Mediators of inflammation,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
March 1992,
Biochemical pharmacology,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
January 2001,
Research communications in molecular pathology and pharmacology,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
February 1984,
Pharmacological research communications,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
October 2005,
Life sciences,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
January 2005,
Drugs in R&D,
G Mehmetçik, and
N Alptekin, and
G Toker, and
M Uysal
January 1984,
Toxicologic pathology,
