BIOMAT Database Logo BIOMAT Database Logo

Difference of anti-complementary effect of double stranded DNA and single stranded DNA. 1977

Y Tsutsui, and I Suzuki

Anti-complementary effect of both native double stranded DNA and denatured single stranded DNA was examined by the use of phage DNA of microgram level. The distinct difference of anti-complementary effect was detected between the double and single stranded DNA, that is, only single stranded DNA showed the anti-complementary effect. It is supposed that that the anti-complementary effect of single stranded DNA revealed by the present study is different from the anti-Clq effect which reported on both double and single stranded DNA by Agnello et al.

UI MeSH Term Description Entries
D003168 Complement Fixation Tests Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1. Complement Absorption Test, Conglutinating,Conglutination Reaction,Conglutinating Complement Absorption Test,Complement Fixation Test,Conglutination Reactions,Fixation Test, Complement,Fixation Tests, Complement,Reaction, Conglutination,Reactions, Conglutination,Test, Complement Fixation,Tests, Complement Fixation
D003172 Complement C1 The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION. C1 Complement,Complement 1,Complement Component 1,C1, Complement,Complement, C1,Component 1, Complement
D004247 DNA A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D004277 DNA, Single-Stranded A single chain of deoxyribonucleotides that occurs in some bacteria and viruses. It usually exists as a covalently closed circle. Single-Stranded DNA,DNA, Single Stranded,Single Stranded DNA

Related Publications

Y Tsutsui, and I Suzuki
Detection of anti-double and anti-single stranded DNA antibodies in chronic liver disease: significance of anti-double stranded DNA antibody in autoimmune hepatitis.
April 1994, Journal of gastroenterology,
Y Tsutsui, and I Suzuki
Abnormal Anionic Porphyrin Sensing Effect for HER2 Gene Related DNA Detection via Impedance Difference between MWCNTs and Single-Stranded DNA or Double-Stranded DNA.
October 2018, Molecules (Basel, Switzerland),
Y Tsutsui, and I Suzuki
Anti-DNA antibodies exhibit different binding motif preferences for single stranded or double stranded DNA.
July 2000, Immunology letters,
Y Tsutsui, and I Suzuki
[Single-stranded fractions of double stranded DNA (author's transl)].
January 1977, Postepy biochemii,
Y Tsutsui, and I Suzuki
Direct sequencing of double-stranded DNA PCR products via removing the complementary strand with single-stranded DNA of an M13 clone.
February 1990, Nucleic acids research,
Y Tsutsui, and I Suzuki
[Isolation of single-stranded DNA, double-stranded RNA-DNA hybrid with anti-nucleic acid antibody coupled affinity column].
September 1986, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
Y Tsutsui, and I Suzuki
Responsive polymer gels: double-stranded versus single-stranded DNA.
September 2007, The journal of physical chemistry. B,
Y Tsutsui, and I Suzuki
An ELISA procedure to detect anti-double-stranded and anti-single-stranded DNA binding antibodies in connective tissue disorders.
January 1990, Journal of clinical laboratory analysis,
Y Tsutsui, and I Suzuki
Induction of immunological tolerance to single-stranded and double-stranded DNA.
September 1982, Scandinavian journal of immunology,
Y Tsutsui, and I Suzuki
Electrodeless dielectrophoresis of single- and double-stranded DNA.
October 2002, Biophysical journal,
Copied contents to your clipboard!