-transparent.png){kind=logo}
Three new observations of trisomy 8 mosaicism are presented. In two postnatal cases, both patients showed agenesis of corpus callosum associated with different clinical findings. In a third case, the prenatal diagnosis revealed trisomy 8 mosaicism exclusively in chorionic villi (CV) cells long term culture. Normal results were obtained in CV direct preparation and in cultured amniotic cells. In lymphocytes, the child showed low level trisomy 8 mosaicism. The only clinical findings were deep palmar and plantar furrows. The present cases as well as reports in the literature indicate that the variation in tissular repartition of normal and trisomic clones in trisomy 8 mosaicism is possibly responsible for the missing correlation between cytogenetic findings and clinical severity in this syndrome.
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
March 1967,
American journal of diseases of children (1960),
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
January 1995,
Cancer genetics and cytogenetics,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
December 1974,
Helvetica paediatrica acta,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
October 1974,
American journal of diseases of children (1960),
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
November 1975,
Humangenetik,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
March 2008,
Pediatric hematology and oncology,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
November 1988,
Clinical pediatrics,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
February 1975,
Archives francaises de pediatrie,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
January 1998,
European journal of human genetics : EJHG,
K Miller, and
A Arslan-Kirchner, and
B Schulze, and
A Dudel-Neujahr, and
M Morlot, and
U Burck, and
F Gerresheim
January 1983,
Klinische Padiatrie,
