Biomaterial Database

On matching compliance between canine carotid arteries and polyurethane grafts. 1997

S Hsu, and H Kambic

Department of Chemical Engineering, Chung Hsing National University, Taichung, Taiwan, ROC.

Compliance mismatch between a host artery and an implanted graft has been suggested as a contributing factor to a small diameter graft failure. In this study, static compliance and dynamic compliance were defined and measured in vitro and in vivo for canine carotid arteries and 2 types of polyurethane grafts. Based on these compliance values, the circumferential modulus (E[theta]) and longitudinal modulus (Ez) were calculated. It was shown that grafts have constant moduli over a wide range of pressure while the moduli of carotid arteries increase significantly with increasing pressure (dynamic E[theta] from 0.20 to 1.32 MPa). Polyurethane grafts are nearly isotropic, with the modulus almost identical in each direction, while carotid arteries are anisotropic (E[theta]/Ez = 2-3). The dynamic moduli are generally higher than static values and are especially pronounced for arteries. Due to these different inherent characteristics, the compliance of a synthetic graft may match that of the host artery only in the circumferential direction and within a small pressure range. A stated limitation is therefore given for complete compliance matching. The results provide a rationale for identifying the degree of compliance match. These efforts may lead to better designed vascular grafts.

UI	MeSH Term	Description	Entries
D008954	Models, Biological	Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.	Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D011140	Polyurethanes	A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.	Polyisocyanates,Ostamer,Pellethane,Spandex,Ostamers,Pellethanes,Polyisocyanate,Polyurethane,Spandices
D011475	Prosthesis Failure	Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.	Prosthesis Loosening,Prosthesis Durability,Prosthesis Migration,Prosthesis Survival,Durabilities, Prosthesis,Durability, Prosthesis,Failure, Prosthesis,Failures, Prosthesis,Loosening, Prosthesis,Loosenings, Prosthesis,Migration, Prosthesis,Migrations, Prosthesis,Prosthesis Durabilities,Prosthesis Failures,Prosthesis Loosenings,Prosthesis Migrations,Prosthesis Survivals,Survival, Prosthesis,Survivals, Prosthesis
D001807	Blood Vessel Prosthesis	Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.	Vascular Prosthesis,Blood Vessel Prostheses,Tissue-Engineered Vascular Graft,Graft, Tissue-Engineered Vascular,Grafts, Tissue-Engineered Vascular,Prostheses, Blood Vessel,Prostheses, Vascular,Prosthesis, Blood Vessel,Prosthesis, Vascular,Tissue Engineered Vascular Graft,Tissue-Engineered Vascular Grafts,Vascular Graft, Tissue-Engineered,Vascular Grafts, Tissue-Engineered,Vascular Prostheses,Vessel Prostheses, Blood,Vessel Prosthesis, Blood
D002339	Carotid Arteries	Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.	Arteries, Carotid,Artery, Carotid,Carotid Artery
D003187	Compliance	Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001672	Biocompatible Materials	Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.	Biomaterials,Bioartificial Materials,Hemocompatible Materials,Bioartificial Material,Biocompatible Material,Biomaterial,Hemocompatible Material,Material, Bioartificial,Material, Biocompatible,Material, Hemocompatible
D001696	Biomechanical Phenomena	The properties, processes, and behavior of biological systems under the action of mechanical forces.	Biomechanics,Kinematics,Biomechanic Phenomena,Mechanobiological Phenomena,Biomechanic,Biomechanic Phenomenas,Phenomena, Biomechanic,Phenomena, Biomechanical,Phenomena, Mechanobiological,Phenomenas, Biomechanic