[Chemotactic monocyte and activation factor (MCAF/MCP1)in material from bronchoalveolar lavage fluid of patients with chronic bronchitis]. 1997

K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
Kliniki Chorób Wewnetrznych i Pneumonologii Instytutu Medycyny Wewnetrznej.

The aim of this study was to evaluate concentrations of monocyte chemotactic and activating factor (MCAF/MCP1) in bronchoalveolar lavage fluid (BAL) from patients with chronic bronchitis. 32 patients (aged 46 +/- 2 years) with chronic bronchitis and 14 patients (aged 30.5 +/- 3.4 years) of control group took part in this study. ELISA test (kits from R&D, USA) was used to measure concentrations of this chemokine in BALF. The results indicate for significant increase of MCAF/MCP1 in BALF from patients with chronic bronchitis (mean +/- SEM = 393 +/- 105.9 pg/ml) as compared from those of control group (middle +/- SEM = 36.4 +/- 10.9 pg/ml). CONCLUSIONS MCAF/MCP1 may participate in creation of inflammatory changes of airways in patients with chronic bronchitis.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001991 Bronchitis Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI. Bronchitides
D001992 Bronchoalveolar Lavage Fluid Washing liquid obtained from irrigation of the lung, including the BRONCHI and the PULMONARY ALVEOLI. It is generally used to assess biochemical, inflammatory, or infection status of the lung. Alveolar Lavage Fluid,Bronchial Lavage Fluid,Lung Lavage Fluid,Bronchial Alveolar Lavage Fluid,Lavage Fluid, Bronchial,Lavage Fluid, Lung,Pulmonary Lavage Fluid,Alveolar Lavage Fluids,Bronchial Lavage Fluids,Bronchoalveolar Lavage Fluids,Lavage Fluid, Alveolar,Lavage Fluid, Bronchoalveolar,Lavage Fluid, Pulmonary,Lavage Fluids, Alveolar,Lavage Fluids, Bronchial,Lavage Fluids, Bronchoalveolar,Lavage Fluids, Lung,Lavage Fluids, Pulmonary,Lung Lavage Fluids,Pulmonary Lavage Fluids
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D004797 Enzyme-Linked Immunosorbent Assay An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D018945 Monocyte Chemoattractant Proteins Chemokines that are chemoattractants for monocytes. These CC chemokines (cysteines adjacent) number at least three including CHEMOKINE CCL2. Monocyte Chemoattractant Protein,Monocyte Chemotactic Protein,Monocyte Chemotactic Proteins,Chemoattractant Protein, Monocyte,Chemoattractant Proteins, Monocyte,Chemotactic Protein, Monocyte,Chemotactic Proteins, Monocyte,Protein, Monocyte Chemoattractant,Protein, Monocyte Chemotactic

Related Publications

K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
January 1997, Journal of investigational allergology & clinical immunology,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
December 1996, Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
January 1987, Acta paediatrica Hungarica,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
July 2005, Journal of thrombosis and haemostasis : JTH,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
January 1995, The Korean journal of internal medicine,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
December 1988, Klinicheskaia meditsina,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
January 1996, The Kurume medical journal,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
September 1985, The American review of respiratory disease,
K Jahnz-Rózyk, and E Borensztejn, and M Faber, and T Płusa, and E Pirozyńska, and Z Pojda
April 1992, Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases,
Copied contents to your clipboard!