Biomaterial Database

Hibernation triggers and cryogens: do they play a role in hibernation? 1997

S Vybíral, and L Janský

Department of Comparative Physiology, Faculty of Science, Charles University, Prague, Czech Republic.

A survey of the literary evidence on cryogens and hibernation induction triggers is given and the results of experiments on the effect of hypothalamic or i.v. injections of opioids and plasma from hibernating European hamsters on body temperature control of rabbits are presented. Pharmacological doses of a delta opioid--DADLE (25 or 50 micrograms), when injected into the anterior hypothalamus, induce a small and short-lasting hypothermic effect in cold exposed rabbits, due to the downward shift of the temperature threshold for shivering. Lower doses (5 micrograms) are without effect, similarly as i.v. administrations (500 micrograms/kg) of this substance. Intrahypothalamic injections of met-enkephalin (0.1-1 microgram) induce a slight hyperthermia due to the shift of all thermoregulatory effectors to higher body temperatures. Intrahypothalamic injections of plasma from hibernating European hamsters do not influence the body temperature control in rabbits.

UI	MeSH Term	Description	Entries
D001833	Body Temperature Regulation	The processes of heating and cooling that an organism uses to control its temperature.	Heat Loss,Thermoregulation,Regulation, Body Temperature,Temperature Regulation, Body,Body Temperature Regulations,Heat Losses,Loss, Heat,Losses, Heat,Regulations, Body Temperature,Temperature Regulations, Body,Thermoregulations
D004745	Enkephalins	One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral nervous systems and in the adrenal medulla.	Enkephalin
D004777	Environment	The external elements and conditions which surround, influence, and affect the life and development of an organism or population.	Environmental Impact,Environmental Impacts,Impact, Environmental,Impacts, Environmental,Environments
D006605	Hibernation	The dormant state in which some warm-blooded animal species pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.	Hibernation, Artificial,Induced Hibernation,Artificial Hibernation,Artificial Hibernations,Hibernation, Induced,Hibernations,Induced Hibernations
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013696	Temperature	The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.	Temperatures