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The development of in vitro experimental chemotherapy against P.carinii has been hindered by the lack of efficient methods for continuous cultivation of the microorganism. Various short-term systems, allowing the production of infectious forms of Pneumocystis, can be employed for in vitro experimental chemotherapy. The purpose of the present study is to describe a statistically relevant algorithmic model for the evaluation of P.carinii in short-term in vitro culture and drug screening.
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