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Addition of antibiotics to bone cement is used more and more in orthopedics and traumatology. Indications are discussed: 1. infection prophylaxis in replacement arthroplasty, 2. therapy and recidive prophylaxis in infected arthroplasty, 3. therapy of chronic osteomyelitis. Our own experiments show release of antibiotics from bone cement Palacos and penetration into cortical bone after experimental osteomyelitis. Carbenicillin and Cephalotin show high level of concentration for 2 weeks, after 3 weeks there is no concentration evident. Lincomycin and Gentamycin in the first days show high tissue levels, after decrease and increase again after second week. Gentamycin was examined during 10 months showing high levels after this time.
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
January 1973,
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M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
December 1978,
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M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
January 1982,
Pathologie-biologie,
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
November 1976,
Archiv fur orthopadische und Unfall-Chirurgie,
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
October 2002,
Journal of chemotherapy (Florence, Italy),
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
November 1976,
The Japanese journal of antibiotics,
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
January 1981,
Unfallchirurgie,
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
January 1984,
Scandinavian journal of gastroenterology. Supplement,
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
March 1980,
Zhonghua wai ke za zhi [Chinese journal of surgery],
M Wannske, and
O Trentz, and
R D Schenck, and
C Weiss
February 1977,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
