BIOMAT Database Logo BIOMAT Database Logo

Possible biochemical mode of anti-inflammatory action of Azadirachta indica A. Juss. in rats. 1998

R R Chattopadhyay
Biometry Research Unit, Indian Statistical Institute, Calcutta, India.

The water soluble part of alcoholic extract of A. indica leaves at a dose of 200 mg/kg, p.o., exerted significant antiinflammatory activity in cotton pellet granuloma assay in rats. The extract also inhibited significantly the biochemical parameters (viz. DNA, RNA, lipid peroxide, acid phosphatase and alkaline phosphatase) studied in cotton pellet exudate.

UI MeSH Term Description Entries
D008297 Male Males
D010936 Plant Extracts Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard. Herbal Medicines,Plant Extract,Extract, Plant,Extracts, Plant,Medicines, Herbal
D010946 Plants, Medicinal Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals. Herbs, Medicinal,Medicinal Herbs,Healing Plants,Medicinal Plants,Pharmaceutical Plants,Healing Plant,Herb, Medicinal,Medicinal Herb,Medicinal Plant,Pharmaceutical Plant,Plant, Healing,Plant, Medicinal,Plant, Pharmaceutical,Plants, Healing,Plants, Pharmaceutical
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000894 Anti-Inflammatory Agents, Non-Steroidal Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Analgesics, Anti-Inflammatory,Aspirin-Like Agent,Aspirin-Like Agents,NSAID,Non-Steroidal Anti-Inflammatory Agent,Non-Steroidal Anti-Inflammatory Agents,Nonsteroidal Anti-Inflammatory Agent,Anti Inflammatory Agents, Nonsteroidal,Antiinflammatory Agents, Non Steroidal,Antiinflammatory Agents, Nonsteroidal,NSAIDs,Nonsteroidal Anti-Inflammatory Agents,Agent, Aspirin-Like,Agent, Non-Steroidal Anti-Inflammatory,Agent, Nonsteroidal Anti-Inflammatory,Anti-Inflammatory Agent, Non-Steroidal,Anti-Inflammatory Agent, Nonsteroidal,Anti-Inflammatory Analgesics,Aspirin Like Agent,Aspirin Like Agents,Non Steroidal Anti Inflammatory Agent,Non Steroidal Anti Inflammatory Agents,Nonsteroidal Anti Inflammatory Agent,Nonsteroidal Anti Inflammatory Agents,Nonsteroidal Antiinflammatory Agents
D017208 Rats, Wistar A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain. Wistar Rat,Rat, Wistar,Wistar Rats
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

R R Chattopadhyay
Molluscicidal activity of neem (Azadirachta indica A. Juss).
May 1996, Journal of ethnopharmacology,
R R Chattopadhyay
Ethnopharmacognostical survey of Azadirachta indica A. Juss (Meliaceae).
October 1991, Journal of ethnopharmacology,
R R Chattopadhyay
Analysis of insecticidal Azadirachta indica A. Juss. fractions.
January 2004, Zeitschrift fur Naturforschung. C, Journal of biosciences,
R R Chattopadhyay
Effects of Azadirachta indica A Juss on some biochemical, immunological and visceral parameters in normal and stressed rats.
December 1992, Indian journal of experimental biology,
R R Chattopadhyay
Quinone reductase inducers in Azadirachta indica A. Juss flowers, and their mechanisms of action.
January 2005, Asian Pacific journal of cancer prevention : APJCP,
R R Chattopadhyay
An Improved Genome Assembly of Azadirachta indica A. Juss.
July 2016, G3 (Bethesda, Md.),
R R Chattopadhyay
Chemistry of the neem tree (Azadirachta indica A. Juss.).
January 1999, Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles,
R R Chattopadhyay
Endophytic actinomycetes from Azadirachta indica A. Juss.: isolation, diversity, and anti-microbial activity.
May 2009, Microbial ecology,
R R Chattopadhyay
Arthropods on Azadirachta indica A. Juss. (Sapindales: Meliaceae) saplings.
January 2022, Brazilian journal of biology = Revista brasleira de biologia,
R R Chattopadhyay
The proteinaceous, gum polysaccharide from Azadirachta indica A. Juss.
December 1971, Carbohydrate research,
Copied contents to your clipboard!