-transparent.png){kind=logo}
BACKGROUND We have previously reported that people who are cocaine-dependent have reduced blue cone b-wave electroretinogram (ERG) responses. In this preliminary study, we examined the relationship between blue cone ERG amplitudes and craving response to cocaine cues. METHODS A new series of 14 recently withdrawn subjects who were cocaine-dependent completed a cocaine craving questionnaire at baseline, and again following exposure to laboratory cues; an ERG was also performed. RESULTS Cocaine-dependent subjects with a blunted ERG blue cone response (< 0.5 microV) showed significantly greater increases in craving following cue-exposure than subjects without the blunted ERG blue cone response. CONCLUSIONS Subjects with a blunted ERG response may represent a subgroup more vulnerable to cocaine craving and relapse.
D A Smelson, and
M Roy, and
A Roy, and
S Santana
February 1996,
Lancet (London, England),
D A Smelson, and
M Roy, and
A Roy, and
S Santana
March 1999,
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
July 2004,
Journal of substance abuse treatment,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
October 1996,
Proceedings of the National Academy of Sciences of the United States of America,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
March 2010,
The American journal of drug and alcohol abuse,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
December 1997,
Drug and alcohol dependence,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
January 1994,
Journal of substance abuse treatment,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
November 2020,
Drug and alcohol dependence,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
December 2006,
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
D A Smelson, and
M Roy, and
A Roy, and
S Santana
November 2011,
Psychopharmacology,
