Efficacy of oxibendazole against adult and larval nematodes of cattle. 1976

J W Crowley, and A C Todd, and D H Bliss, and T J Kennedy

Calves which were artificially infected with Haemonchus, Ostertagia, Trichostrongylus, Cooperia, and Oesophagostomum but which were also carrying natural infections of Nematodirus and Trichuris were treated with 15.0 mg of oxibendazole (methyl-5-n-propoxy-2-benzimidazole-carbamate)/kg of body weight at 3 days, 7 days, and 42 days after exposure to the infective trichostrongylid and strongylid larvae. Efficacies against adult populations of these genera treated on day 42, except Trichostrongylus, exceeded 98%. The chemical was highly effective against immature nematodes of the genera, except Oesophagostomum (0%). Data were not obtained on Trichostrongylus. The oxibendazole premix was palatable, and toxicosis due to the chemical was not seen in these calves.

UI MeSH Term Description Entries
D009349 Nematode Infections Infections by nematodes, general or unspecified. Infections, Nematode,Infection, Nematode,Nematode Infection
D002219 Carbamates Derivatives of carbamic acid, H2NC( Carbamate,Aminoformic Acids,Carbamic Acids,Acids, Aminoformic,Acids, Carbamic
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418 Cattle Diseases Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus. Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000871 Anthelmintics Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. Anthelmintic,Antihelmintic,Vermifuge,Vermifuges,Antihelmintics
D001562 Benzimidazoles Compounds with a BENZENE fused to IMIDAZOLES.

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