Biomaterial Database

Esophageal elastance in awake and anesthetized recumbent dogs. 1976

Y L Lai, and J R Rodarte, and R E Hyatt

Esophageal elastance was measured in trained dogs placed in the prone, supine, and left lateral postures before and during sodium thiopental anesthesia. Esophageal elastance was measured from static pressure-volume curves and during spontaneous breathing at functional residual capacity. There was a significant decrease in esophageal elastance, estimated from the pressure-volume curves, during anesthesia in both prone and lateral positions but not in the supine posture. Changes in vagal tone produced by stimulation of the vagal nerves did not alter esophageal elastance. Therefore, underlying mechanisms for these changes in esophageal elastance are not fully understood. There was an increase in esophageal elastance when lung volumes increased from 55 to 80% total lung capacity. However, we did not find a significant change in esophageal elastance between awake and anesthetized conditions or between positions during spontaneous breathing at functional residual capacity.

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D008176	Lung Volume Measurements	Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.	Lung Capacities,Lung Volumes,Capacity, Lung,Lung Capacity,Lung Volume,Lung Volume Measurement,Measurement, Lung Volume,Volume, Lung
D011187	Posture	The position or physical attitude of the body.	Postures
D002642	Chick Embryo	The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.	Embryo, Chick,Chick Embryos,Embryos, Chick
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004548	Elasticity	Resistance and recovery from distortion of shape.
D004947	Esophagus	The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
D000758	Anesthesia	A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia