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In 17 patients (15 women, 2 men) with acute intermittent porphyria in the incidence of 23 clinical symptoms during 49 attacks was calculated. The most frequent symptoms in percentage of attacks were: Red colour of the urine 100%, abdominal pain 92%, tachycardia 88%, hypertension 75%, vomiting 54%, peripheral neuropathy 50%. In 35% of acute attacks a transient normochromic, normocytic anemia developed which is probably due to a disturbance of heme synthesis. Oliguria was found in 25%, azotemia in 12.5% of attacks. 4 patients with an average of 5 preceding acute attacks showed a persistent reduction of renal function during the symptom-free interval, in contrast to 12 patients with an average of 1.7 previous attacks and normal renal function. During the observation period from 1960-1974 3 (= 18%) of the 17 patients died.
G Schley, and
M Anlauf, and
K D Bock
January 1981,
Zentralblatt fur Gynakologie,
G Schley, and
M Anlauf, and
K D Bock
June 1979,
Medicina clinica,
G Schley, and
M Anlauf, and
K D Bock
August 1979,
Bratislavske lekarske listy,
G Schley, and
M Anlauf, and
K D Bock
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Revista brasileira de pesquisas medicas e biologicas,
G Schley, and
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January 1980,
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G Schley, and
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K D Bock
October 1981,
Wiener klinische Wochenschrift,
G Schley, and
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December 1981,
Medicina clinica,
G Schley, and
M Anlauf, and
K D Bock
February 1981,
Anasthesie, Intensivtherapie, Notfallmedizin,
G Schley, and
M Anlauf, and
K D Bock
January 2022,
Translational gastroenterology and hepatology,
G Schley, and
M Anlauf, and
K D Bock
March 1991,
BMJ (Clinical research ed.),
