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Oligonucleotide separations with capillary gel electrophoresis. 1992

A Paulus
Ciba-Geigy Ltd., Central Research, Basel, Switzerland.

Capillary Electrophoresis with polyacrylamide gel filled columns offers a fast and automated alternative to slab gel electrophoresis for the analysis of biopolymers. The principle of operation of CE in general, the operation conditions for the analysis of synthetic oligonucleotides and practical examples are described.

UI MeSH Term Description Entries
D009841 Oligonucleotides Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed) Oligonucleotide
D004591 Electrophoresis, Polyacrylamide Gel Electrophoresis in which a polyacrylamide gel is used as the diffusion medium. Polyacrylamide Gel Electrophoresis,SDS-PAGE,Sodium Dodecyl Sulfate-PAGE,Gel Electrophoresis, Polyacrylamide,SDS PAGE,Sodium Dodecyl Sulfate PAGE,Sodium Dodecyl Sulfate-PAGEs

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