Biomaterial Database

A novel microwave recipe for an antibiofilm titanium surface. 2015

Judy Gopal, and Venkatesan Nandakumar, and Mukesh Doble

Bioengineering and Drug Design Lab, Department of Biotechnology, Indian Institute of Technology-Madras, Chennai 600036, India; Department of Molecular Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea.

A microwave based method for the surface modification of titanium was demonstrated for biomedical applications. The surfaces were characterized using XRD, HR-SEM and Goniometer. The absence of rutile, anatase and brookite phases and the presence of an amorphous near-native oxide film were confirmed. The microwave oxidized (MWO) surfaces exhibited a significant antibiofilm activity against Escherichia coli and Staphylococcus aureus. In the presence and absence of the water pot, the oxidation times of 60 and 20min demonstrated a high antibiofilm property respectively. The surfaces turned more hydrophobic with increasing oxidation time. The viability of L6 cells remained unaffected on the MWO oxidized surfaces, signifying no loss in biocompatibility. This systematic study presents MWO as a promising technique for solving the biofilm problem faced by the otherwise robust titanium.

UI	MeSH Term	Description	Entries
D008872	Microwaves	That portion of the electromagnetic spectrum from the UHF (ultrahigh frequency) radio waves and extending into the INFRARED RAYS frequencies.	EHF Waves,Extremely High Frequency Radio Waves,Micro Wave,Micro Waves,Ultrahigh Frequency Waves,Microwave Radiation,EHF Wave,Micro Waves,Microwave,Microwave Radiations,Radiation, Microwave,Ultrahigh Frequency Wave,Wave, EHF,Wave, Micro,Wave, Ultrahigh Frequency,Waves, Micro
D004926	Escherichia coli	A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.	Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D013211	Staphylococcus aureus	Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
D013499	Surface Properties	Characteristics or attributes of the outer boundaries of objects, including molecules.	Properties, Surface,Property, Surface,Surface Property
D014025	Titanium	A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.
D018441	Biofilms	Encrustations formed from microbes (bacteria, algae, fungi, plankton, or protozoa) embedded in an EXTRACELLULAR POLYMERIC SUBSTANCE MATRIX that is secreted by the microbes. They occur on body surfaces such as teeth (DENTAL DEPOSITS); inanimate objects, and bodies of water. Biofilms are prevented from forming by treating surfaces with DENTIFRICES; DISINFECTANTS; ANTI-INFECTIVE AGENTS; and anti-fouling agents.	Biofilm