-transparent.png){kind=logo}
Vincristine, prednisone and L-asparaginase in the induction of remission in children with acute lymphoblastic leukemia following relapse. 1978
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
Two hundred and twenty-seven children with recurrent acute lymphoblastic leukemia were treated with various combinations of vincristine, prednisone, cyclophosphamide and L-asparaginase in an approach to the induction of remission. The combination of L-asparaginase 1,000 mu/kg iv q.d. x 10, vincristine 2.0 mg/m2iv q.w. x 4 and prednisone 40 mg/m2 p.o.q.d. x 28 days was found to be highly effective. The incidence of remission was 73%. No significant improvement was achieved when cyclophosphamide was added to this regimen. Various combinations of cytosine arabinoside, cyclophosphamide, vincristine, prednisone, BCNU or CCNU failed to maintain remission duration for more than two or three months. Neither BCNU nor CCNU prevented the development of CNS leukemia.
Related Publications
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
January 1976,
Medical and pediatric oncology,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
January 1979,
Medical and pediatric oncology,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
May 1983,
Cancer treatment reports,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
February 1977,
Cancer research,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
June 1976,
La Nouvelle presse medicale,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
January 2014,
Case reports in oncological medicine,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
January 1977,
Oncology,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
April 2000,
Cancer,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
December 1969,
British medical journal,
F H Kung, and
W L Nythan, and
J Cuttner, and
G Falkson, and
P Lanzkowsky, and
V Del Duca, and
I U Nawabi, and
K Koch, and
H Pluess, and
A Freeman, and
E O Burgert, and
L A Leone, and
F Ruymann, and
R B Patterson, and
T Degnan, and
N Hakami, and
T F Pajak, and
J Holland
March 1976,
Cancer,
