| D007113 |
Immunity, Innate |
The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS. |
Immunity, Native,Immunity, Natural,Immunity, Non-Specific,Resistance, Natural,Innate Immune Response,Innate Immunity,Immune Response, Innate,Immune Responses, Innate,Immunity, Non Specific,Innate Immune Responses,Native Immunity,Natural Immunity,Natural Resistance,Non-Specific Immunity |
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| D008264 |
Macrophages |
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.) |
Bone Marrow-Derived Macrophages,Monocyte-Derived Macrophages,Macrophage,Macrophages, Monocyte-Derived,Bone Marrow Derived Macrophages,Bone Marrow-Derived Macrophage,Macrophage, Bone Marrow-Derived,Macrophage, Monocyte-Derived,Macrophages, Bone Marrow-Derived,Macrophages, Monocyte Derived,Monocyte Derived Macrophages,Monocyte-Derived Macrophage |
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| D003048 |
Coccidiosis |
Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA. |
Besnoitiasis,Besnoitiosis,Besnoitiases,Besnoitioses,Coccidioses |
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| D003593 |
Cytoplasm |
The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990) |
Protoplasm,Cytoplasms,Protoplasms |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D000074084 |
THP-1 Cells |
A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport. |
THP-1 Cell Line,Cell Line, THP-1,Cell Lines, THP-1,Cell, THP-1,Cells, THP-1,THP 1 Cell Line,THP 1 Cells,THP-1 Cell,THP-1 Cell Lines |
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| D016207 |
Cytokines |
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner. |
Cytokine |
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| D054804 |
Cathelicidins |
Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes. |
ALL-38 Peptide,Antibacterial Peptide LL-37,Antimicrobial Peptide LL-37,Bac4 Protein, Bos taurus,CAP18 Lipopolysaccharide-Binding Protein,CATH-1 Protein,Cathelicidin,Cathelicidin 1,Cathelicidin Antimicrobial Peptide,Cathelicidin LL-37,Cathelicidin-1,Cathelin-Like Protein,Cathelin-Related Antimicrobial Peptide,LL-37 Antibacterial Peptide,LL-37 Peptide,Myeloid Cathelicidin 1 Protein, Equus caballus,Ropocamptide,eCATH-1,hCAP-18,CAP-18,CAP18,FA-LL-37,K9CATH,eCATH-1 protein, Equus caballus,ALL 38 Peptide,Antibacterial Peptide LL 37,Antibacterial Peptide, LL-37,Antimicrobial Peptide LL 37,Antimicrobial Peptide, Cathelin-Related,CAP 18,CAP18 Lipopolysaccharide Binding Protein,CATH 1 Protein,Cathelicidin LL 37,FA LL 37,LL 37 Antibacterial Peptide,LL 37 Peptide,LL-37, Antibacterial Peptide,LL-37, Antimicrobial Peptide,LL-37, Cathelicidin,Lipopolysaccharide-Binding Protein, CAP18,Peptide LL-37, Antibacterial,Peptide LL-37, Antimicrobial,Peptide, ALL-38,Peptide, Cathelin-Related Antimicrobial,Peptide, LL-37,Peptide, LL-37 Antibacterial,Protein, CAP18 Lipopolysaccharide-Binding,Protein, CATH-1,Protein, Cathelin-Like,eCATH 1,eCATH 1 protein, Equus caballus,hCAP 18 |
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| D018688 |
Neospora |
A genus of protozoan parasites of the subclass COCCIDIA. Its species are parasitic in dogs, cattle, goats, and sheep, among others. N. caninum, a species that mainly infects dogs, is intracellular in neural and other cells of the body, multiplies by endodyogeny, has no parasitophorous vacuole, and has numerous rhoptries. It is known to cause lesions in many tissues, especially the brain and spinal cord as well as abortion in the expectant mother. |
Neospora caninum,Neospora caninums,Neosporas,caninums, Neospora |
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| D019950 |
Mitogen-Activated Protein Kinase 1 |
A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. |
Extracellular Signal-Regulated Kinase 2,MAP Kinase 2,Mitogen-Activated Protein Kinase 2,p42 MAP Kinase,p42 MAPK,p42(Mitogen-Activated Protein Kinase),MAPK1 Mitogen-Activated Protein Kinase,MAPK2 Mitogen-Activated Protein Kinase,p42(Mapk),p42(Mapk) Kinase,Extracellular Signal Regulated Kinase 2,MAP Kinase, p42,MAPK1 Mitogen Activated Protein Kinase,MAPK2 Mitogen Activated Protein Kinase,Mitogen Activated Protein Kinase 1,Mitogen Activated Protein Kinase 2 |
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