Nucleotide metabolism regulates human telomere length via telomerase activation.
2023
Tracy M Bryan
Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, Australia. tbryan@cmri.org.au.
UI
MeSH Term
Description
Entries
D009711
Nucleotides
The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Nucleotide
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D016615
Telomere
A terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability. Its length is believed to be a few hundred base pairs.
Telomeres
D059505
Telomere Homeostasis
Maintenance of TELOMERE length. During DNA REPLICATION, chromosome ends loose some of their telomere sequence (TELOMERE SHORTENING.) Various cellular mechanism are involved in repairing, extending, and recapping the telomere ends.