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Renin substrate in plasma from normal and biolaterally nephrectomized rats was measured using an excess of rat or rabbit renin which had the same pressor activity when directly assayed in the rat. The amounts of angiotensin I generated with an excess of rat renin were similar to those generated with an excess of rabbit renin in plasma from normal and bilaterally nephrectomized rats. Further addition of an excess of homologous renin to the incubation mixture did not generate more angiotensin I from normal and bilaterally nephrectomized rat plasma which had been incubated before with an excess of rabbit renin. The isoelectric focusing profiles of plasma renin substrate from normal and bilaterally nephrectomized rats were almost identical using an excess of either rat or rabbit renin. It is concluded that there is no species-specific renin substrate for homologous renin in normal or bilaterally nephrectomized rats.
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
January 1969,
Helvetica medica acta. Supplementum,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
July 1976,
Acta pharmacologica et toxicologica,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
September 1991,
Canadian journal of physiology and pharmacology,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
July 1968,
The American journal of physiology,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
May 1975,
Nihon Jinzo Gakkai shi,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
January 1972,
Acta pathologica et microbiologica Scandinavica. Section A, Pathology,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
September 1991,
Canadian journal of physiology and pharmacology,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
June 1975,
Circulation research,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
April 1951,
The American journal of physiology,
K Hiwada, and
H Tanaka, and
E Murakami, and
M Ono, and
T Kokubu
August 1981,
Journal of pharmacobio-dynamics,
