Selection in dioecious populations. 1979

T Nagylaki

Weak selection at a single mutiallelic locus in a dioecious population is analysed under the assumptions of panmixia and discrete non-overlapping generations. The results hold for both autosomal and X-linked loci after several generations have elapsed. With an error of the order of s (i.e. O(s)), where s is the selection intensity, the population evolves as if it were monoecious. The equivalent monoecious fitnesses must be calculated by weighting each sex by the number of genes carried by an individual at the locus under consideration. Provided the explicit time dependence (if any) of the genotypic fitnesses in each sex is O(s2), the rate of change of the male--female allelic frequency differences is O(s2). If the change per generation of the genotypic fitnesses is smaller than second order in s (i.e. o(s2)), then to O(s2) the rate of change of the unweighted average of the male and female mean fitnesses is equal to the genic variance. Hence, as long as there is significant gene frequency change, this measure of the mean fitness of the population will increase.

UI MeSH Term Description Entries
D008297 Male Males
D002874 Chromosome Mapping Any method used for determining the location of and relative distances between genes on a chromosome. Gene Mapping,Linkage Mapping,Genome Mapping,Chromosome Mappings,Gene Mappings,Genome Mappings,Linkage Mappings,Mapping, Chromosome,Mapping, Gene,Mapping, Genome,Mapping, Linkage,Mappings, Chromosome,Mappings, Gene,Mappings, Genome,Mappings, Linkage
D005260 Female Females
D005787 Gene Frequency The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION. Allele Frequency,Genetic Equilibrium,Equilibrium, Genetic,Allele Frequencies,Frequencies, Allele,Frequencies, Gene,Frequency, Allele,Frequency, Gene,Gene Frequencies
D005838 Genotype The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS. Genogroup,Genogroups,Genotypes
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000483 Alleles Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product. Allelomorphs,Allele,Allelomorph
D012641 Selection, Genetic Differential and non-random reproduction of different genotypes, operating to alter the gene frequencies within a population. Natural Selection,Genetic Selection,Selection, Natural
D014960 X Chromosome The female sex chromosome, being the differential sex chromosome carried by half the male gametes and all female gametes in human and other male-heterogametic species. Chromosome, X,Chromosomes, X,X Chromosomes

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