BIOMAT Database Logo BIOMAT Database Logo

Adjuvant activity of synthetic N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds on cell-mediated cytotoxicity in syngeneic mice. 1977

T Igarashi, and M Okada, and I Azuma, and Y Yamamura

UI MeSH Term Description Entries
D009374 Neoplasms, Experimental Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. Experimental Neoplasms,Experimental Neoplasm,Neoplasm, Experimental
D003602 Cytotoxicity, Immunologic The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement. Tumoricidal Activity, Immunologic,Immunologic Cytotoxicity,Immunologic Tumoricidal Activities,Immunologic Tumoricidal Activity,Tumoricidal Activities, Immunologic
D006020 Glycopeptides Proteins which contain carbohydrate groups attached covalently to the polypeptide chain. The protein moiety is the predominant group with the carbohydrate making up only a small percentage of the total weight. Glycopeptide
D000276 Adjuvants, Immunologic Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. Immunoactivators,Immunoadjuvant,Immunoadjuvants,Immunologic Adjuvant,Immunopotentiator,Immunopotentiators,Immunostimulant,Immunostimulants,Adjuvant, Immunologic,Adjuvants, Immunological,Immunologic Adjuvants,Immunological Adjuvant,Adjuvant, Immunological,Immunological Adjuvants

Related Publications

T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds.
June 1978, Infection and immunity,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Mitogenic activity of adjuvant-active N-acetylmuramyl-L-alanyl-D-isoglutamine and its analogues.
June 1977, Biken journal,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Adjuvant activity of mycoloyl derivatives of N-acetylmuramyl-L-alanyl-D-isoglutamine in mice and guinea pigs.
January 1979, Microbiology and immunology,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Study of immunomodulatory properties of N-acetylmuramyl-L-alanyl-D-isoglutamine and N-acetylglucosaminyl-(beta 1----4)-N-acetylmuramyl-L-alanyl-D-isoglutamine.
January 1991, Biomedical science,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Higher immunoadjuvant activities of N-acetyl-beta-D-glucosaminyl-(1-4)-N-acetylmuramyl-L-alanyl-D-isoglutamine in comparison with N-acetylmuramyl-L-alanyl-D-isoglutamine.
January 1979, Microbiology and immunology,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Chemical synthesis and adjuvant activity of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) analogs 1, 2.
June 1981, Chemical & pharmaceutical bulletin,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Immunoadjuvant effects of the synthetic muramyl-dipeptide (MDP) N-acetylmuramyl-L-alanyl-D-isoglutamine.
October 1978, Zeitschrift fur Immunitatsforschung. Immunobiology,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Adjuvant activity of 6-O-mycoloyl derivatives of N-acetylmuramyl-L-seryl-D-isoglutamine and related compounds in mice and guinea pigs.
April 1979, Infection and immunity,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Possible chemotaxis of human monocytes by N-acetylmuramyl-L-alanyl-D-isoglutamine.
January 1983, Infection and immunity,
T Igarashi, and M Okada, and I Azuma, and Y Yamamura
Stereo-isomer specific induction of renal cell apoptosis by synthetic muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine).
July 2002, Molecular and cellular biochemistry,
Copied contents to your clipboard!