-transparent.png){kind=logo}
Using radioautography and immunocytochemistry, we investigated differences in 3H-cytidine incorporation into RNA in vasopressin or neurophysin-positive neurons in the rat hypothalamus following adrenalectomy. Control animals and those that had been bilaterally adrenalectomized for 2 weeks received 0.3 mCi 3H-cytidine subcutaneously and were decapitated 1 h following injection. Brains were prepared for combined radioautography and immunocytochemistry. Incorporation was estimated by counting silver grains over immunoreactive neurons. The neurons of the paraventricular nucleus (PVN) showed a consistent and significant increase in the amount of incorporation of label 2 weeks after bilateral adrenalectomy. There was no change in incorporation in neurons of either the supraoptic or suprachiasmatic nuclei. These findings suggest that the vasopressin PVN neurons, some of which project to the zona externa of the median eminence, are activated under conditions of adrenalectomy.
A J Silverman, and
C A Gadde, and
E A Zimmerman
December 1985,
Brain research,
A J Silverman, and
C A Gadde, and
E A Zimmerman
February 1979,
Cell and tissue research,
A J Silverman, and
C A Gadde, and
E A Zimmerman
November 1975,
Brain research,
A J Silverman, and
C A Gadde, and
E A Zimmerman
January 1975,
Cell and tissue research,
A J Silverman, and
C A Gadde, and
E A Zimmerman
July 1977,
Endocrinology,
A J Silverman, and
C A Gadde, and
E A Zimmerman
October 1978,
Endocrinology,
A J Silverman, and
C A Gadde, and
E A Zimmerman
May 1981,
The Journal of comparative neurology,
A J Silverman, and
C A Gadde, and
E A Zimmerman
November 1978,
The American journal of anatomy,
A J Silverman, and
C A Gadde, and
E A Zimmerman
July 1976,
Kidney international,
A J Silverman, and
C A Gadde, and
E A Zimmerman
October 1983,
Neuroscience letters,
