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When injected intramuscularly in a dose of 10, 20 and 40 proteolytic units terrilitin stimulates the immune response to sheep red blood cells (SRBC). Red cells of rats injected with terrilitin also stimulate the immune response to SRBC in intact syngeneic recipients. Splenocytes of rats injected with terrilitin secrete helper factor to the cultural medium. Supernatant of splenocytes incubated in the presence of red cells of rats injected with terrilitin possess more demonstrable immunostimulant properties than supernatant of splenocytes incubated with or without red cells of intact rats. Splenocytes of rats injected with red cells of rats pretreated with protease form the helper factor. Rat red blood cells treated with serum of animals given terrilitin are capable of inducing the production of the helper factor by splenocytes.
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
September 1972,
Problemy gematologii i perelivaniia krovi,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
January 1982,
Annali dell'Istituto superiore di sanita,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
January 1997,
Vestnik Rossiiskoi akademii meditsinskikh nauk,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
January 1999,
Vestnik Rossiiskoi akademii meditsinskikh nauk,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
January 1986,
Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
January 1995,
Eksperimental'naia i klinicheskaia farmakologiia,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
August 1988,
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic],
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
December 1992,
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic],
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
July 1990,
Pharmazie in unserer Zeit,
G A Chalyĭ, and
L G Prokopenko, and
L P Chalaia
January 1997,
Pneumonologia i alergologia polska,
