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We studied the effect of acute short-term exercise on insulin binding to erythrocytes in plasma with non-insulin dependent diabetes mellitus and normal controls. In the normal controls, insulin binding was increased immediately after the exercise and returned to the basal level at 30 min after the exercise. This increase was due to an affinity change without any change in the insulin receptor number. In contrast, insulin binding tended to decrease in the diabetics after the exercise, and this change was due to a decreased affinity without any change in the number of insulin receptors. These results indicate that the control mechanism of insulin receptor affinity in response to exercise is different in non-insulin dependent diabetics and normals.
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
January 1988,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
August 1983,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
April 1988,
Clinical and investigative medicine. Medecine clinique et experimentale,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
November 1982,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
January 1987,
Diabetes research and clinical practice,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
January 1987,
Diabetes care,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
December 1983,
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
October 1981,
Acta medica Okayama,
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
March 1983,
British medical journal (Clinical research ed.),
M Iwasaki, and
M Kobayashi, and
S Ohgaku, and
H Maegawa, and
Y Shigeta
January 1984,
Clinical and investigative medicine. Medecine clinique et experimentale,
