Comparison of hydroxylamine, 4-dimethylaminophenol and nitrite protection against cyanide poisoning in mice.
1982
R Kruszyna, and
H Kruszyna, and
R P Smith
UI
MeSH Term
Description
Entries
D007928
Lethal Dose 50
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
LD50,Dose 50, Lethal
D008297
Male
Males
D008708
Methemoglobinemia
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
Methemoglobinemias
D009573
Nitrites
Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M
Nitrite
D003486
Cyanides
Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.
Cyanide,Isocyanide,Isocyanides
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006898
Hydroxylamines
Organic compounds that contain the (-NH2OH) radical.
D000627
Aminophenols
Phenols substituted in any position by an amino group.
Hydroxyanilines
D000818
Animals
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.
Animal,Metazoa,Animalia
D000906
Antibodies
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).