Biomaterial Database

Preparation of 11C-methyl iodide and L-[S-methyl-11C]methionine by an automated continuous flow process. 1982

J Davis, and Y Yano, and J Cahoon, and T F Budinger

A continuous flow procedure has been developed for the synthesis of 11C-methyl iodide and L-[S-methyl-11C]methionine from 11CO2. The preparation can be completed in 20 min after the end of bombardment. This procedure results in the production of approximately 44 mCi 11C-methyl methionine with a specific activity of 3.3 Ci/mmol. Radiochemical purity is greater than 96%. The procedure has been automated so that the preparation can be carried out remotely, thus minimizing exposure of personnel to radiation.

UI	MeSH Term	Description	Entries
D007553	Isotope Labeling	Techniques for labeling a substance with a stable or radioactive isotope. It is not used for articles involving labeled substances unless the methods of labeling are substantively discussed. Tracers that may be labeled include chemical substances, cells, or microorganisms.	Isotope Labeling, Stable,Isotope-Coded Affinity Tagging,Isotopically-Coded Affinity Tagging,Affinity Tagging, Isotope-Coded,Affinity Tagging, Isotopically-Coded,Isotope Coded Affinity Tagging,Labeling, Isotope,Labeling, Stable Isotope,Stable Isotope Labeling,Tagging, Isotope-Coded Affinity,Tagging, Isotopically-Coded Affinity
D002250	Carbon Radioisotopes	Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.	Radioisotopes, Carbon
D006847	Hydrocarbons, Iodinated	Hydrocarbon compounds with one or more HYDROGEN atoms substituted with IODINE.	Iodinated Hydrocarbons
D014814	Vitamin U	A vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract.	Methionine Methylsulfonium Chloride,Methylmethioninesulfonium Chloride,Methylmethionine,Methylmethionine Sulfonium Chloride,S-Methylmethionine,Sulfonium, ((3S)-3-Amino-3-Carboxypropyl)Dimethyl-, Inner Salt,Chloride, Methionine Methylsulfonium,Chloride, Methylmethioninesulfonium,Methylsulfonium Chloride, Methionine,S Methylmethionine
D014815	Vitamins	Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.	Vitamin