| D007328 |
Insulin |
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). |
Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin |
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| D008297 |
Male |
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Males |
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| D009994 |
Osmolar Concentration |
The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent. |
Ionic Strength,Osmolality,Osmolarity,Concentration, Osmolar,Concentrations, Osmolar,Ionic Strengths,Osmolalities,Osmolar Concentrations,Osmolarities,Strength, Ionic,Strengths, Ionic |
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| D002648 |
Child |
A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. |
Children |
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| D003922 |
Diabetes Mellitus, Type 1 |
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. |
Diabetes Mellitus, Brittle,Diabetes Mellitus, Insulin-Dependent,Diabetes Mellitus, Juvenile-Onset,Diabetes Mellitus, Ketosis-Prone,Diabetes Mellitus, Sudden-Onset,Diabetes, Autoimmune,IDDM,Autoimmune Diabetes,Diabetes Mellitus, Insulin-Dependent, 1,Diabetes Mellitus, Type I,Insulin-Dependent Diabetes Mellitus 1,Juvenile-Onset Diabetes,Type 1 Diabetes,Type 1 Diabetes Mellitus,Brittle Diabetes Mellitus,Diabetes Mellitus, Insulin Dependent,Diabetes Mellitus, Juvenile Onset,Diabetes Mellitus, Ketosis Prone,Diabetes Mellitus, Sudden Onset,Diabetes, Juvenile-Onset,Diabetes, Type 1,Insulin Dependent Diabetes Mellitus 1,Insulin-Dependent Diabetes Mellitus,Juvenile Onset Diabetes,Juvenile-Onset Diabetes Mellitus,Ketosis-Prone Diabetes Mellitus,Sudden-Onset Diabetes Mellitus |
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| D003926 |
Diabetic Coma |
A state of unconsciousness as a complication of diabetes mellitus. It occurs in cases of extreme HYPERGLYCEMIA or extreme HYPOGLYCEMIA as a complication of INSULIN therapy. |
Coma, Diabetic,Comas, Diabetic,Diabetic Comas |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D006944 |
Hyperglycemic Hyperosmolar Nonketotic Coma |
A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed consciousness leading to COMA in the absence of KETOSIS and ACIDOSIS. |
Coma, Hyperglycemic Hyperosmolar Nonketotic,Hyperosmolar Hyperglycemic Nonketotic Coma,Hyperosmolar Hyperglycemic State,Hyperosmolar Hyperglycemic Syndrome,Hyperosmolar Nonketotic Coma,Nonketotic Hyperglycemic Coma,Nonketotic Hyperosmolar Coma,Coma, Hyperosmolar Nonketotic,Coma, Nonketotic Hyperglycemic,Coma, Nonketotic Hyperosmolar,Comas, Hyperosmolar Nonketotic,Comas, Nonketotic Hyperosmolar,Hyperglycemic Coma, Nonketotic,Hyperglycemic State, Hyperosmolar,Hyperglycemic States, Hyperosmolar,Hyperglycemic Syndrome, Hyperosmolar,Hyperglycemic Syndromes, Hyperosmolar,Hyperosmolar Coma, Nonketotic,Hyperosmolar Comas, Nonketotic,Hyperosmolar Hyperglycemic States,Hyperosmolar Hyperglycemic Syndromes,Hyperosmolar Nonketotic Comas,Nonketotic Coma, Hyperosmolar,Nonketotic Comas, Hyperosmolar,Nonketotic Hyperosmolar Comas,Syndrome, Hyperosmolar Hyperglycemic,Syndromes, Hyperosmolar Hyperglycemic |
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| D013997 |
Time Factors |
Elements of limited time intervals, contributing to particular results or situations. |
Time Series,Factor, Time,Time Factor |
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