Biomaterial Database

Confirmation of brain death using 99m Tc HM-PAO. 1994

W Adelstein

University of Missouri Hospital and Clinics, Division of Neurosurgery, Columbia 65212.

Because 99m Tc HM-PAO is simple to use, noninvasive and readily available, it appears to satisfy most criteria for the use of radionuclide cerebral imaging in the confirmation of brain death. Waiting periods, which are often included in brain death protocols, delay the diagnosis of brain death. 99m Tc HM-PAO has proven to be a useful test to confirm brain death.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010091	Oximes	Compounds that contain the radical R2C	Aldoximes,Hydroxyimino Compounds,Ketoxime,Ketoximes,Oxime,Compounds, Hydroxyimino
D010347	Patient Care Planning	Usually a written medical and nursing care program designed for a particular patient.	Nursing Care Plans,Goals of Care,Plans, Nursing Care,Care Goal,Care Goals,Care Plan, Nursing,Care Planning, Patient,Care Plans, Nursing,Nursing Care Plan,Plan, Nursing Care,Planning, Patient Care
D011877	Radionuclide Imaging	The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.	Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D001926	Brain Death	A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)	Brain Dead,Coma Depasse,Irreversible Coma,Brain Deads,Coma, Irreversible,Death, Brain
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D015609	Organotechnetium Compounds	Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.	Compounds, Organotechnetium
D019690	Technetium Tc 99m Exametazime	A gamma-emitting RADIONUCLIDE IMAGING agent used in the evaluation of regional cerebral blood flow and in non-invasive dynamic biodistribution studies and MYOCARDIAL PERFUSION IMAGING. It has also been used to label leukocytes in the investigation of INFLAMMATORY BOWEL DISEASES.	Tc-99m HMPAO,Technetium Tc 99m Hexamethylpropyleneamine Oxime,99m-Tc-HMPAO,99mTc-HMPAO,Ceretec,Tc-99m-Exametazime,Tc-99m-Hexamethylpropyleneamine Oxime,Technetium Tc 99m Hexamethylpropylene-amine Oxime,Tc 99m Exametazime,Tc 99m Hexamethylpropyleneamine Oxime,Technetium Tc 99m Hexamethylpropylene amine Oxime