-transparent.png){kind=logo}
The influence on nerve regeneration of the extracellular matrix glycoprotein laminin was studied after sciatic nerve transection in 90 outbred Sprague-Dawley rats. Nerve regeneration through basal lamina grafts was comparable with regeneration through traditional nerve grafts across gaps up to 2.0 cm in length. True axonal regeneration rather than axonal branching was demonstrated by retrograde horseradish peroxidase labeling of nerve cables. Pretreatment of basal lamina grafts with antilaminin antibodies reduced the total number of regenerated axons by 90 percent with a significant decrease of nerve conduction velocity and a significant impairment of walking track patterns. The basement membrane glycoprotein laminin serves a critical role in the regeneration of peripheral nerves through basal lamina grafts.
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
August 1995,
Journal of hand surgery (Edinburgh, Scotland),
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
December 1991,
Experimental neurology,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
February 2005,
Cryobiology,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
December 1983,
Brain research,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
January 1990,
Progress in neurobiology,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
April 2003,
The Journal of biological chemistry,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
January 1992,
Brain research,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
January 1993,
Exercise and sport sciences reviews,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
April 1983,
Archivum histologicum Japonicum = Nihon soshikigaku kiroku,
D J Bryan, and
R A Miller, and
P D Costas, and
K K Wang, and
B R Seckel
March 1986,
The Journal of cell biology,
