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A transient arrest of arterial blood flow can be accomplished by intra-arterial injection of a new type of degradable microsphere. The effects of single and multiple injections of these microspheres into rat hepatic arteries were studied by measurements of fractional cardiac output distribution and 133Xe washout from the liver before and after embolization. Injection of these microspheres into the hepatic artery caused a significant but transient reduction of the arterial blood flow to the liver. Repetition of the injection several times over several days produced identical effects on each embolization. No signs of hepatic cell damage were detected after repeated embolization, as suggested by assay of the serum enzymes or the Bromsulphalein retention test.
B Lindell, and
K F Aronsen, and
U Rothman
October 1985,
Gan to kagaku ryoho. Cancer & chemotherapy,
B Lindell, and
K F Aronsen, and
U Rothman
December 1987,
Nuclear medicine communications,
B Lindell, and
K F Aronsen, and
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January 1985,
Acta chirurgica Scandinavica,
B Lindell, and
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July 1989,
The British journal of surgery,
B Lindell, and
K F Aronsen, and
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August 1988,
Gan to kagaku ryoho. Cancer & chemotherapy,
B Lindell, and
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January 1991,
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group,
B Lindell, and
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April 1989,
Nihon Gan Chiryo Gakkai shi,
B Lindell, and
K F Aronsen, and
U Rothman
April 2015,
Cardiovascular and interventional radiology,
B Lindell, and
K F Aronsen, and
U Rothman
August 1988,
Gan to kagaku ryoho. Cancer & chemotherapy,
B Lindell, and
K F Aronsen, and
U Rothman
November 1977,
Acta radiologica: diagnosis,
